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A dinner party turns deadly when a group of friends are trapped inside of their house after a massive alien invasion threatens to take over the world. Things take a turn for the worse when they discover that the chemical the military is using to destroy the aliens is also turning humans into zombie-like savages.
Alex, a troubled young man is thrust into a dark underworld when he becomes a pawn in a brutal struggle between two drug lords for a new street drug called Loco. Alex's only hope comes from a beautiful girl, Lydia, who is also caught up in the scheme, and together they try to escape their dangerous world. A shocking surprise awaits them because nothing is what it seems to be in the world of Loco.
A terminally ill man gets his buddy to bust him out of the hospital. But, in the process, the duo antagonizes a city policeman, who trails them to the boonies surrounding their hometown. The local sheriff and their lady friend (who think more kindly of the pair) strive to find the fugitives before the less-compassionate posse, which includes a deranged, rifle-toting foe of the two.
When the zombie apocalypse arrives, groups of survivors band together to defend themselves at any cost. Unfortunately for the remaining few, zombies have evolved into different species altogether and exist not just in this dimension but in a dimension of their own. With little hope, the humans gather strength for one last chance at saving their world in this intensely twisted anthology.